Autografts of Bone Marrow in Dogs After Lethal Total-Body Radiation
نویسندگان
چکیده
منابع مشابه
Autografts of bone marrow in dogs after lethal total-body radiation.
LPEN AND BAUM have shown that infusions of autobogous marrow induce recovery in dogs after exposure of the entire body to 400 or 600 r of 250 kv x-rays.1 The purpose of this communication is to report that recovery in dogs can be induced promptly by autobogous marrow infusion after exposure to x-ray or gamma radiation in dosages up to 1500 r. Both hone marrow and lyrnphoid tissue are restored. ...
متن کاملHomografts of bone marrow in dogs after lethal total-body radiation.
IFE-SAVING HOMOGRAFTS of bone marrow after lethal whole-body irradiation usually succeed in rodents1 but fail in dogs.2’3 Recently we reported a successful and life-saving hornograft of marrow after 1,200 roentgens of total-body irradiation in a beagle.4 Success was attributed to the following procedures : ( 1 ) use of a donor and a recipient with a close genetic relationship (litter-mates ), (...
متن کاملTotal-body irradiation for bone marrow transplantation.
Total-body irradiation (TBI), when given as part of bone marrow transplantation (BMT), works by enhancing immune suppression and by exerting a tumoricidal effect. The modality has been made less toxic because of new approaches to delivering TBI, such as fractionation, and partial organ shielding, Colleen Lawton, MD, professor at the Medical College of Wisconsin, Milwaukee, said at the 1998 Amer...
متن کاملGastrointestinal decontamination of dogs treated with total body irradiation and bone marrow transplantation.
Procedures for total and selective gastrointestinal decontamination of dogs are described. The selective procedure removed only Gram negative aerobic bacteria, yeast and fungi. Dogs receiving total decontamination were less susceptible to the GI syndrome following total body irradiation (TBI) than dogs receiving conventional care. After TBI and allogeneic bone marrow transplantation, serum albu...
متن کاملProlonged Disease-Free Survival in Dogs With Lymphoma After Total-Body Irradiation and Autologous Marrow Transplantation
Dogs with spontaneous lymphoma were treated with one of three aggressive treatment protocols: (1) combination chemotherapy with cyclophosphamide, L-asparaginase. Oncovin#{174}, and prednisone (CLOP); (2) combination chemotherapy with nitrogen mustard, Oncovin#{174}, prednisone, 1-asparaginase, and 6-mercaptopurine (MOPA-6); or (3) MOPA-6 followed by total-body irradiation (TBI) and autologous m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 1960
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v15.2.255.255